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Such drugs include certain antihistamines, tranquilizers, barbiturates, and monoamine oxidase inhibitors.ĭiphenoxylate should not be used in animals with known hypersensitivity or allergy to the drug. Consult with your veterinarian to determine if other drugs your pet is receiving could interact with diphenoxylate. The most common adverse effects are constipation and sedation.ĭiphenoxylate may interact with other medications.

While generally safe and effective when prescribed by a veterinarian, diphenoxylate can cause side effects in some animals. Potential Side Effects of Diphenoxylate in Dogs

Human formulations: Logen® (Goldline), Lomotil® (Searle), Lonox® (Geneva) and various generic brands.ĭiphenoxylate is available in 2.5 milligram tablets or liquid (combined with atropine).

This drug is registered for use in humans only. This drug is not approved for use in animals by the Food and Drug Administration but it is prescribed legally by veterinarians as an extra-label drug. Diphenoxylate slows the gastrointestinal tract, decreases intestinal secretions and enhances absorption of liquids.ĭiphenoxylate is a prescription drug and can only be obtained from a veterinarian or by prescription from a veterinarian.

Diphenoxylate, also known as Logen®, Lomotil®, and Lonox®, is primarily used to treat diarrhea and colitis in dogs and cats. Diphenoxylate belongs to a class of drugs known as opiate agonists (morphine derivative).